Combined Allergic bronchopulmonary mycosis and Eosinophilic Granulomatosis with Polyangiitis: A Case Report and Literature Review

Abstract

Abstract Background: Several diagnostic criteria are common for Allergic bronchopulmonary mycosis (ABPM) and eosinophilic granulomatosis with polyangiitis (EGPA). There were few reports of cases where ABPM and EGPA coexist. Here, we present a patient who simultaneously met the diagnostic criteria for both ABPM and EGPA. Case presentation: A 27-year-old female visited our hospital with a history of asthma, peripheral blood eosinophilia, increased total IgE, Aspergillus fumigatus specific IgE, reversible mild bronchiectasis, sinusitis, bronchial mucus plugs and cultivation of Aspergillus from bronchoalveolar lavage fluid. Furthermore, glucocorticoids therapy is effective. Conclusions: These results met the diagnostic criteria for both ABPM and EGPA. We also reviewed several reported cases of coexistence of ABPM and EGPA so far. Special attention should be paid to the possibility of both diseases coexisting in the disease process.