Prognostic Factors in Patients with Cirrhosis

Author:

Rasheed Modar Haj1,Aldouh Maher1,Aldeen Mohammad Assd1,Ali Ayman2

Affiliation:

1. Faculty of medicine, Syrian Private University

2. Department of Internal medicine, Faculty of Medicine, Syrian Private University, Damascus, Syria

Abstract

Abstract Background Cirrhosis is defined by fibrosis and nodule development in the liver as a result of persistent damage, changing the liver lobule's natural structure. Portal hypertension and hyperdynamic circulation are the key factors that contribute to morbidity and death in cirrhotic individuals. Secondary to cirrhosis and alterations in intrahepatic and systemic vascular structures that lead to the creation of collateral circulation and hyperdynamic circulation, portal hypertension occurs. We want to correlate the most significant cirrhosis prognostic indicators with many of the ocular characteristics we looked at in this study. Methods In this cross-sectional study, 319 liver cirrhosis patients who received care at Damascus Hospital between 2015 and 2022 made up the sample. Results According to the findings, there is a statistically significant link between prognosis and both the Child Pugh index and patient symptoms (P < 0.05). Regarding the association between prognosis and the patient's vital signs, age, and duration of hospital stay, we were unable to detect any association between these factors. Conclusion In order to keep patients with cirrhosis from progressing to later stages of the illness, it is important to evaluate them early. The prognosis of patients was worsened by the more disturbed the Child Pugh criteria were.

Publisher

Research Square Platform LLC

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