Affiliation:
1. North Eastern Regional Institute of Science and Technology
Abstract
Abstract
A simple, new and solvent free route to the regioselective and stereoselective synthesis of (E)- and (Z)- allylamines has been achieved by the reaction of Baylis-Hillman acetates with various nitrogen nucleophiles in the presence of 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU). This method requires very short reaction time and accomplished by SN2ʹ nucleophilic substitution pathway.
Publisher
Research Square Platform LLC