Feasibility of Oropharyngeal pH-metry in diagnosing LPR – A single centre experience

Abstract

Abstract Purpose: Laryngopharyngeal reflux (LPR) is commonly diagnosed based on symptoms, nonspecific clinical findings, or positive response to empirical treatment. This single centre data highlights the role of Oropharyngeal pH-metry (Restech®) in diagnosing LPR and its practicality as an alternative to Hypopharyngeal-esophageal multichannel intraluminal impedance-pH monitoring (HEMII-pH). Methods: A retrospective data of patients who underwent Oropharyngeal pH-metry (Restech®) at Department of Otorhinolaryngology Head and Neck Surgery, Center Hospitalier de Luxembourg Eich, Luxembourg from January 2022 until November 2022. 66 patients with probable LPR symptoms with suggestive flexible scope findings were included in the study. Results: 66 patients consist of 29 male and 37 female patients (43.94%, 56.06% respectively). The median age is 51.5 ranges from 16 to 87 years old. A positive RYAN score demonstrated in 38 (57.57%) patients while negative RYAN score demonstrated in 28 (42.42%) patients. Furthermore, 24(36.36%) patients showed severe LPR, 28(42.42%) moderate and 12(18.18%) mild, 1(1.52%) no LPR and 1(1.52%) neutral LPR. Throat discomfort and irritative cough were the main symptoms reported by the patients. Proton pump inhibitor such as Pantoprazole and Esomeprazole were the common medications given to treat LPR. The dose given is either 20mg twice daily or 40mg twice daily depending on the severity of the LPR. Conclusion: Oropharyngeal pH-metry (Restech®) is a feasible tool as an alternative to HEMII-pH in evaluating LPR.