Oral Health and Metabolic Syndrome: A population-based Persian Cohort Study

Abstract

Abstract Introduction: The most prevalent oral condition is tooth decay. Prior research sometimes points to a connection between certain systemic disorders and dental health state. Nevertheless, it is still debatable whether metabolic syndrome (Mets) poses a danger? As a result, the present study was carried out to explore the connection between DMFT and the MetS and its components. Method: This cross-sectional study was done on 10606 people aged 40 to 70 who participated in phase I of the Persian Kharameh cohort study from 2014 to 2017. Mets was defined according to the IDF definition. Multiple logistic and Poisson regression were conducted to evaluate the relationship between DMFT and MetS (its components). Moreover, the Random Forest model was used to depict the importance of covariates on the relationship with MetS and its components. Results: The mean age of the participants was 51.94 ± 8.27 years. Of the 10663 participants in the Kharameh cohort study, 4719 cases were males (44.26%). After controlling of confounders, with increasing DMFT, the odds of hypertension, elevated fasting plasma glucose, and reduced HDL cholesterol increased. Additionally, the random forest model showed that DMFT was an effective factor for central obesity and high blood pressure. Conclusion: The findings of this research demonstrated a significant relationship between DMFT and hypertension, elevated fasting plasma glucose, and reduced HDL cholesterol. Additionally, DMFT is more effective on the main components of MetS: central obesity and blood pressure than on MetS.