An alternative simple method of assessment of clinical agreement of two methods of measuring blood glucose level without Bland–Altman limits

Abstract

Abstract New methods of measuring blood glucose levels are generally accepted when they show sufficient agreement with the existing established method. Such agreement is almost always assessed by Bland-Altman (B-A) method. This method of assessing agreement has several limitations such as this does not assess the degree of agreement and it requires uniform clinical tolerance limits. We describe a simple and robust method of assessing the agreement between two methods of measuring blood glucose levels that directly uses the clinical tolerance limits and assesses the degree of agreement without calculating the B-A limits. This alternative is more flexible also as the clinical tolerance limits can be varyingly set to provide more accuracy at critical values of the blood glucose level and relaxed at not-so-critical