Effect on Cardiac function in digestive system’s cancer with or without acute kidney injury patients using a non-invasive assessment of impedance cardiography: a retrospective cohort study

Abstract

Abstract Objectives This study’s objective was to explore the possibility of clinical evaluation of digestive system’s cancer with or without AKI patients’ cardiac function measured by impedance cardiography (ICG, Bioz. Cardio Dynamics, USA); then, try to analyze the possible reason of cardiac function changing, and to approach the independent risk factors for it. Methods Patients who were admitted to the Fourth hospital of Hebei Medical University, China between May 1st, 2019 and February 15th, 2022 were involved. A total of 51 patients with digestive system’s cancer with AKI or without AKI (31 men and 20 women, mean age 61.1 ± 10.9 year) were evaluated to routine ICG. Of the total, 19 patients were assessed to both ultrasound cardiography (UCG) and ICG. Result There were significant positive correlation with the cardiac function parameters, such as cardiac output (CO), cardiac index (CI), stroke volume (SV), left cardiac work index (LCWI) and ejection fraction (EF), measured by ICG and UCG. The relationship was observed between COICG and COUCG (r = 0.707, P = 0.001); CIICG and CIUCG (r = 0.718, P = 0.001); SVICG and SVUCG (r = 0.837, P < 0.001); LCWIICG and EFUCG (r = 0.540, P = 0.017). The cardiac function parameters measured by ICG were statistically significant between cancer with AKI and without AKI patients (P < 0.05). A multivariate analysis revealed that AKI had independent effects on digestive system’s cancer patients’ cardiac function. Conclusions ICG and UCG methods were significant positive correlation with the cardiac function of digestive system’s cancer patients with or without AKI; the cardiac function of digestive system’s cancer with AKI was worse than that of without AKI patients; AKI was the independent risk factor for cardiac function in digestive system’s cancer patients.