Complete resolution of acute abamectin toxicity; a deep dive into the pathophysiology leading to appropriate management: A case report

Author:

Sadiq Rizwan1,Anjum Muhammad Mehwar1,Mian Muhammad Umar2,Rizwan Muhammad1,Butt Aqsa Aamir1

Affiliation:

1. Shaikh Zayed Hospital

2. Allama Iqbal Medical College

Abstract

Abstract

Abamectin toxicity in humans is an uncommon but potentially fatal cause of pesticide poisoning. In this case report, a 14-year-old boy drank almost 50 ml of 1.8% Abamectin pesticide spray. Based on the history given by his brother, the patient initially got irritable with a strong smell of poison and froth coming out of his mouth. At the time of presentation in the Emergency Department (ED), the patient was vomiting and then gradually developed altered mental status with hypotension, tachycardia, hyperaemic conjunctiva, and dermal erythema. He was treated symptomatically with antihistamines, steroids, fluids, and vaso-active agents. His vitals stabilised within 24 hours of the intake and after 3 days of hospital stay including 2 days of observation, he was discharged in good condition with complete recovery. Although abamectin intoxication has a higher threshold for toxicity in humans, there are still an increasing number of cases of it. Consumption of substantial amounts can still prove to be fatal. There is a lack of literature and research on its mechanism of toxicity, pathophysiology, or management guidelines. Yet cases like this are managed based on supportive principles with complete recovery and no sequelae.

Publisher

Springer Science and Business Media LLC

Reference19 articles.

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