Innovative i-PRF semisurgical method for gingival augmentation and root coverage in thin periodontal phenotypes: A preliminary study

Abstract

Abstract Objectives The aim of this study was to evaluate the effect of injectable platelet-rich fibrin (i-PRF) on gingival thickness (GT) and gingival recession (GR) in individuals with thin periodontal phenotypes using a semisurgical approach.Materials and methods In this prospective study, i-PRF was applied via a semisurgical method to augment 53 tooth regions with thin periodontal phenotypes. i-PRF injection was applied to the relevant areas in 4 sessions at an interval of 10 days. GT, GR, keratinized tissue width and periodontal parameters were also recorded before treatment and at 6 months after the last injection.Results A statistically significant difference was observed in GT and GR values at the end of the study compared to baseline. Accordingly, an increase in GT was achieved in 92.5% of the areas treated with i-PRF, and the desired GT (0.8 mm) was achieved in 44.9% of these areas. In addition, significant reductions in the amount of recession were observed in 83.3% of the 12 GR areas (p = 0.005). Moreover, complete coverage was achieved in 60% of these regions.Conclusion With the new i-PRF semisurgical method, which we introduced in this first preliminary study, we showed that GT can be increased in tooth regions with thin gingiva and that areas of GR can be covered. Further comprehensive studies are needed to fully understand the role of i-PRF in enhancing angiogenesis and the histoconductive properties of this fully autogenous blood concentrate.Clinical relevance Classical periodontal plastic surgery applications cannot give predictable results in areas with thin periodontal phenotypes, especially in the case of bone dehiscence and fenestration. In some cases, undesirable progressive GR in these tooth regions also draws attention. With this new i-PRF semisurgical method, successful and predictable treatments can be applied in tooth areas with thin gingiva by increasing angiogenesis and taking advantage of the histoconductive properties of i-PRF.