Affiliation:
1. Inonu University
2. Malatya Turgut Özal University
3. Elazığ Fethi Sekin City Hospital
Abstract
Abstract
Background/Aims:
In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats.
Material and Methods:
This study was conducted in 38 rats, they were divided in to 5 groups and 14 days study periot.
Results, and Conclusions:
When considering biochemical and histopathological results; we were seen that before and after PH 7 days duration and used dozes of both drugs was not sufficient and also higher dozes and at least 10 days periot may be necessary. Althought some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. For future research -at higher dozes and durations- may be found effective.
Publisher
Research Square Platform LLC
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