Global Trends in Research of Coronary Microvascular Dysfunction Over Past Two Decades: A Bibliometric Analysis

Abstract

Abstract After a successful percutaneous coronary intervention, a large number of patients with acute coronary syndrome are still suffering from coronary microvascular dysfunction (CMD), which has become a global health threat. Over the past two decades, CMD-related studies have increased rapidly. This field, however, lacks bibliometric studies. In this research, we used bibliometric analysis to summarize hotspots and trends in scientific and clinical research on CMD. Web of Science Core Collection database was used to collect CMD-related research. Each study was analyzed bibliometrically and visually. CiteSpace and VOSviewer software were performed to generate knowledge maps. Over the past two decades, research on CMD has exploded. Scholars have concentrated on the long-term effects of CMD on a variety of cardiovascular disorders with poor prognoses, such as acute myocardial infarction and heart failure. In the meantime, despite the availability of many invasive and non-invasive tests, the anticipatory detection of CMD during the hypoperfusion phase of myocardial ischemia may be the windfall of future research.