Therapeutic Choices for Ovulatory Dysfunctional Abnormal Uterine Bleeding: A Cross-sectional Study in Chinese Women

Abstract

Abstract Background Ovulatory dysfunction is the primary cause of abnormal uterine bleeding (AUB); however, data on nationwide therapeutic choices of Chinese women are lacking. The aim of this study was to investigate the therapeutic choices of ovulatory dysfunctional abnormal uterine bleeding (AUB-O) in Chinese women and analyse the factors on the selection results.Methods This was a cross-sectional study involving 3527 patients with AUB-O diagnosed by local doctor between 14 and 55 years old. We used questionnaire compiled according to the Chinese AUB-O treatment guidelines to collect the demographic and therapeutic information. Their therapeutic choices were regarded as generally representative of the nation ’s choices.Results The patients were divided into the juvenile group (14–18 years old, n = 84), the reproductive group (19–39 years old, n = 2962) and the senior group (perimenopausal period: 40–55 years old, n = 481). The results showed that irregular menstruation (37.6% − 46.3%), dysmenorrhea (29.9% − 44.4%), and heavy menstrual bleeding (16.7% − 32.2%) were the main symptoms in Chinese AUB-O patients of different ages. Most of the patients chose to seek help in the Department of General Gynecology (78.6% − 90.7%). Among the therapeutic options, combined oral contraceptives (COCs), such as Yasmin I and Yasmin II, met the treatment expectations with high acceptance among patients (36.6%-52.2%).Conclusions It is important to strengthen the endocrine diagnosis ability of doctors in the Department of General Gynecology. With rational education and clinical applications, COCs are expected to become a more prevalent therapeutic option for AUB-O.