Abstract
Abstract
Background
Acute cardiovascular emergencies, including ST-segment elevation myocardial infarction (STEMI) and acute ischemic stroke, are common conditions requiring timely medical intervention. Thrombolytic therapy is an important treatment option for these conditions, although its effectiveness depends on prompt hospital arrival. This study aimed to assess the arrival time and associated factors in patients with ACS-STEMI at the Jimma Medical Center, with the objective of determining the need and applicability of thrombolytic therapy.
Methodology
: This hospital-based cross-sectional study was conducted at the Jimma Medical Center between September 1st and January 30, 2023. All patients diagnosed with ACS-STEMI during the study period were included. Data were collected using structured questionnaires and were entered into Epi-data version 3.1 for analysis. Chi-square tests and logistic regression models were used to examine the relationships between the variables.
Results
Among 63 patients admitted with ACS-STEMI, males accounted for 57.1%, and 42,9% of all admissions were in the 55—64 age group. More than two-thirds of the participants did not attend formal education, and hence could not read and write, and most (68%) used public transport to reach the medical center. Most participants had a very low monthly income of less than 50 USD. Approximately 62% of the study participants arrived at the Medical Center 12 h after the onset of chest pain (average time of arrival was approximately 33 h and 21 min). The sudden onset of symptoms and proximity to the Medical Center (within 5 km) were related to a shorter time of arrival, while those with diabetes mellitus had a longer time of arrival.
Conclusion
The time of arrival was longer in the patients with ACS-STEMI. Level of education, misinterpretation of symptoms, and lack of public health insurance were the major correlates of prehospital delays. This emphasizes the need to improve public health literacy, health insurance coverage, and the availability of standby emergency public ambulances, which shortens the time-to-needle and leads to early medical intervention that reduces morbidity and mortality, while improving survival and quality of life.
Publisher
Research Square Platform LLC
Reference16 articles.
1. What is a Heart Attack? | American Heart Association. Accessed July 5., 2023. https://www.heart.org/en/health-topics/heart-attack/about-heart-attacks.
2. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials;Keeley EC;Lancet,2003
3. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke;Hacke W;N Engl J Med,2008
4. 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaborat;Antman EM;Circulation,2008
5. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines;O’gara PT;Circulation,2013