Improving Pain, Function and Quality of Life in End-Stage Knee Osteoarthritis: A Prospective Cohort Study of Whole-Body Vibration and Exercise as Bridging Therapies for Total Knee Replacement

Author:

Choi Kendrew Yu-Hei1,Chau Wai-Wang2,Li Linda Man-Kuen1,Ng Sammie Yuk-Lam1,Lo Boie Po-Yee1,Ong Michael Tim-Yun2,Yung Patrick Shu-Hang2

Affiliation:

1. Prince of Wales Hospital

2. Chinese University of Hong Kong

Abstract

Abstract Introduction: We prospectively evaluated the effects of exercise and whole-body vibration (WBV) on pain and function in 517 patients with end-stage knee osteoarthritis awaiting total knee replacement (TKR). Methods: Participants were allocated to control (n=201), supervised physiotherapist-led exercise (n=227), or exercise + WBV (n=89) groups. The exercise and exercise + WBV groups completed 4 to 5 group exercise sessions and individualized home exercises. The exercise + WBV group also received 10 minutes of WBV with each session. Outcome measures included pain, self-reported physical function, range of motion, gait, and functional tests. Results: Both exercise groups showed significant improvements in pain, Knee Society Score, knee function, Timed Up and Go test, and functional reach. The exercise + WBV group showed greater improvements in the Knee Injury and Osteoarthritis Outcome Score (KOOS) and KOOS subscales of Pain, Symptoms, and Quality of Life compared to exercise alone. Discussion and Conclusion: Exercise and WBV may substantially improve pain and function for patients awaiting TKR. Targeted, optimized programs could help address needs during prolonged surgical waits and merit investigation. The potential benefits of WBV, including improved pain, symptoms, and quality of life, warrant further study to determine long-term impact and cost-effectiveness. This could support implementing effective approaches to alleviate the impact of delays for TKR. For patients with end-stage knee osteoarthritis awaiting surgery, supervised exercise therapy, especially with WBV, shows promise for reducing pain and improving function. This could bridge a critical gap for those experiencing prolonged waits for TKR.

Publisher

Research Square Platform LLC

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