Orthodontic Treatment under Endodontic Consideration Based on Orthodontic Root Resorption: A Systematic Review and Meta-analysis

Abstract

Abstract Introduction The purpose of this systematic review was to research the difference between root-filled teeth (RFT) and vital pulp teeth (VPT) in orthodontic root resorption (ORR) situations and to offer suggestions for clinicians on therapeutic sequence and timing when considering combined treatment of endodontic and orthodontic. Materials and methods An electronic search of published studies was conducted before November 2022 in PubMed, Web of Science and other databases. Eligibility criteria were based on the Population, Intervention, Comparison, Outcome, and Study design (PICOS) framework. RevMan 5.3 software was used for statistical analysis. Single-factor meta-regression analysis was used to explore the sources of literature heterogeneity, and a random effects model was used for analysis. Results This meta-analysis contained eight studies and ten sets of data. A random effects model was used due to significant heterogeneity among the studies. The funnel plot of the random effects model exhibited a symmetrical distribution, which indicates no publication bias of the included studies. The ORR rate of RFT was significantly lower than that of VPT. Conclusions Endodontic treatment should be carried out first when both endodontic and orthodontic treatments are needed. The timing of orthodontic tooth movement after root canal therapy should be determined by the healing degree of periapical lesions and the severity of trauma if the teeth were injured.