Acute Kidney Injury In Pediatric Burn Patients

Abstract

Abstract Objective: Acute kidney injury (AKI) is a common and important complication of burn injury. Although there are numerous adult studies data regarding AKI in pediatric burn patients is scarce. In this study we aimed to evaluate the frequency, clinical features and prognosis of AKI among pediatric burn injury patients. Methods: This is a retrospective cohort study. Patients aged between 1 month and 18 years followed in pediatric burn intensive care unit between years 2011 and 2017 were included in the study.Patients with known kidney disease were not included. Demographic data, laboratory and clinical variables, management strategies and prognosis were obtained from the hospital records of the patients. Factors associated with AKI were determined by logistic regression analysis. Results: A total of 697 patients had been followed up and among them 87 (12.5%) had acute kidney injury. Older age, being a refugee, prolonged duration between the incident and time of hospitalization, presence of sepsis and severity and type of burn, the amount of fluid administered, being intubated, accompanying organ failure were all related with the development of AKI. According to multivariate logistic regression analysis the most important contributors of AKI were older age and increased serum hemoglobin values. Conclusion: As observed in adults AKI is also an important and common complication of burn injury among pediatric burn patients. Early recognition and prompt and appropriate management is crucial to avoid morbidity and mortality.