The intersecting effects of race, wealth, and education on AIDS incidence, mortality, and case-fatality rate: a Brazilian cohort study of 28.3 million individuals

Author:

Lua Iracema1ORCID,Magno Laio2ORCID,Silva Andréa3ORCID,Pinto Priscila3,Bastos João Luiz4,Jesus Gabriela5,Coelho Ronaldo6,Ichihara Maria7,Barreto Mauricio8,Santos Carlos Teles9,Moucheraud Corrina10,Gorbach Pamina11,Macinko James12ORCID,Souza Luis13,Dourado Inês14,Rasella Davide15ORCID

Affiliation:

1. Institute of Collective Health, Federal University of Bahia (UFBA); Department of Health, State University of Feira de Santana (UEFS)

2. Department of Life Sciences, State University of Bahia (UNEB). Institute of Collective Health, Federal University of Bahia (UFBA).

3. Institute of Collective Health, Federal University of Bahia; Center for Data and Knowledge Integration for Health (CIDACS), Gonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvado

4. Faculty of Health Sciences, Simon Fraser University

5. Faculty of Medicine, Federal University of Bahia (UFBA)

6. Department of Chronic Conditions, Diseases, and Sexually Transmitted Infections at the Brazilian Ministry of Health

7. The Center for Data and Knowledge Integration for Health (CIDACS), Oswaldo Cruz Foundation (FIOCRUZ)

8. Center for Data and Knowledge Integration for Health (CIDACS), Gonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ)

9. Institute of Collective Health, Federal University of Bahia, Salvador, Brazil; Center for Data and Knowledge Integration for Health (CIDACS), Fiocruz, Salvador, Brazil

10. Departments of Health Policy and Management and Community Health Sciences, UCLA Fielding School of Public Health

11. Department of Epidemiology, UCLA Fielding School of Public Health

12. Department of Health Policy and Management, University of California

13. Institute of Collective Health, Federal University of Bahia (UFBA).

14. Institute of Collective Health, Federal University of Bahia (UFBA)

15. ISGlobal

Abstract

Abstract

The relationships between race, education, wealth, their intersections and AIDS morbidity/mortality were analyzed in retrospective cohort of 28.3 million individuals followed for 9 years (2007-2015). Together with several sensitivity analyses, a wide range of interactions on additive and multiplicative scales were estimated. Race, education, and wealth were each strongly associated with all of the AIDS-related outcomes, and the magnitude of the associations increased as intersections were included. A significantly higher risk of illness (aRR: 3.07, 95%CI:2.67-3.53) and death (aRR: 4.96, 95%CI:3.99-6.16) from AIDS was observed at the intersection of Black race, lower educational attainment, and less wealth. A higher case-fatality rate (aRR: 1.62, 95%CI:1.18-2.21) was also seen for the same intersectional group. Historically oppressed groups lying at the intersections of race, education, and wealth, had a considerably higher risk of illness and death from AIDS. AIDS-related interventions will require the implementation of comprehensive intersectoral policies that follow an intersectionality perspective.

Publisher

Research Square Platform LLC

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