The Charlson Age Comorbidity Index Associated with Geriatric Patient’s Mortality after Emergency Surgery: A prospective National Multicenter Study

Author:

Isngadi Isngadi1,Asmoro Aswoco A1,Hariyanto Achmad1,Siswagama Taufiq A1,Rehatta Nancy M2,Chandra Susilo3,Sari Djayanti4,Lestari Mayang I5,Senapathi Tjokorda GA6,Nurdin Haizah7,Wirabuana Belindo2,Pramodana Bintang3,Pradhana Adinda P6,Anggraeni Novita8,Sikumbang Kenanga M8,Halimi Radian A9,Jasa Zafrullah K10,Nasution Akhyar Hamonangan11,Mochamat Mochamat12,Purwoko Purwoko13

Affiliation:

1. Brawijaya University/ Dr. Saiful Anwar General Hospital

2. Airlangga University/ Dr. Soetomo General Hospital

3. University of Indonesia, Cipto Mangunkusumo General Hospital

4. Gadjah Mada University/ Dr. Sardjito General Hospital

5. Sriwijaya University/ Dr. Mohammed Hoesin General Hospital

6. Udayana University/ Sanglah General Hospital

7. Hasanuddin University/ Dr. Wahidin Sudirohusodo General Hospital

8. Riau University/ Arifin Achmad General Hospital

9. Lambung Mangkurat University, Ulin General Hospital

10. Padjadjaran University/ Dr. Hasan Sadikin General Hospital

11. Universitas Sumatera Utara/ Dr. Adam Malik General Hospital

12. Diponegoro University/ Dr. Kariadi General Hospital

13. Sebelas Maret University Faculty of Medicine

Abstract

Abstract Background Aging is an irreversible, progressive and cumulative process that involves biological, anatomical, physiological, and functional changes that occur over a period of time. Emergency surgery in geriatrics is challenging due to the limited time for surgery planning. Charlson Age Comorbidity Index (CACI) can be used as a predictor of mortality in geriatric patients undergoing surgery. The study’s aim is to determine the association between CACI and mortality in geriatric patients undergoing emergency surgery. Methods This study was a prospective analytic observational multicenter study. This study was conducted from February 2021 to April 2021. This study used the whole sampling method and was followed up 30 days after surgery. The data were analyzed using regression and the ROC Curve test with a confidence interval of 95%. Results We obtained 116 geriatric patients undergoing emergency surgery with a 30-day mortality rate of 11.2%. CACI significantly correlated with 30 day-mortality in geriatric underwent emergency surgery (p = 0.000) with B = 4.831. The AUC of the CACI score was 0.966, with a cut-off value of 5.5. For geriatric patients with CACI scores > 5.5, the risk of mortality within 30 days of treatment is 125.33 times greater (95% CI: 14.58–1077.67) than for patients with CACI scores < 5.5. Conclusion CACI is associated with 30-day mortality in geriatric patients undergoing emergency surgery. CACI score also could be used to predict 30-day mortality in geriatric underwent emergency surgery.

Publisher

Research Square Platform LLC

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