Affiliation:
1. HMC Westeinde Stichting Haaglanden Medisch Centrum: HMC Westeinde
2. Leiden University Medical Center: Leids Universitair Medisch Centrum
3. MCH Westeinde: Medisch Centrum Haaglanden
4. Medical Centre Haaglanden: Medisch Centrum Haaglanden
Abstract
Abstract
Tuberculosis (TB) is a disease with a high burden, with most patients in low and middle income countries (LMIC). In Western countries however, this disease is rare, but with the increasing number of migrants it becomes more relevant. Especially in women with fertility issues, TB is not the most likely diagnosis and therefore difficult to discover and treat. If TB is not detected at an early stage, it can have major consequences for fertility and pregnancy outcomes. Screening should be suggested in women originated from high endemic countries with unexplained fertility loss, or during first trimester screening. QuantiFERON testing and PCR sampling for TB should be the golden standard. This case report describes fertility issues and an immature delivery in a young woman caused by extrapulmonary TB in the genital tract. With this case report, we hope to draw attention to this disease so that early detection can take place and serious outcome can be prevented.
Publisher
Research Square Platform LLC
Reference18 articles.
1. Global tuberculosis report 2020. Licence: CC BY-NC-SA 3.0 IGO. Geneva: World Health Organization; 2020.
2. Slump E, Erkens CGM, van Hunen R, Schimmel HJ, van Soolingen D, de Vries G. Tuberculose in Nederland 2017: surveillancerapport inclusief rapportage monitoring van interventies. RIVM Rapport 2017 – 0140. Bilthoven: RIVM; 2017.
3. WHO. (2019). Consolidated guidelines on drug-resistant tuberculosis treatment. Geneva: World Health Organization; 2019
4. Sarah M. Lyon1, Milton D. Rossman2,Pulmonary Tuberculosis Pathogenesis, February 2017 Volume 5 Issue 1 5.1.24 DOI: 10.1128/microbiolspec.TNMI7-0032-2016
5. JoAnne L, Flynn J, Chan T. Latency and reactivation, July 2001, American society for microbiology Volume 69, Issue 7 DOI: 10.1128/IAI.69.7.4195-4201.2001