Opportunistic screening for COPD among socially marginalized patients

Author:

Brünés Nina1,Lindstroem Mette Bendtz2,Ulrik Charlotte Suppli3,Andersen Ove2,Lisby Marianne4,Godtfredsen Nina Skavlan3,Hansen Tina Leth1,Pisinger Charlotta5,Graven Vibeke6,Marsaa Kristoffer7,Thomsen Laura Hohwü3

Affiliation:

1. Department of Quality and Patient Care, Copenhagen University Hospital, Amager and Hvidovre

2. Department of Clinical Research, Copenhagen University Hospital, Amager and Hvidovre

3. Department of Respiratory Medicine, Copenhagen University Hospital, Amager and Hvidovre

4. Research Center for Emergency Medicine, Department of Clinical Medicine, Aarhus University, Health

5. Center for Clinical Research and Prevention, Copenhagen University Hospital, Bispebjerg and Frederiksberg

6. REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital

7. Department of Multidisease, Copenhagen University Hospital – North Zealand

Abstract

Abstract Background Chronic obstructive pulmonary disease (COPD) is a common disease associated with premature death. Tobacco exposure is the main risk factor, but lower socioeconomic status, early life insults, and occupational exposures are also among the risk factors. Smoking cessation and early detection of COPD are crucial in order to improve outcomes. Socially marginalized people, facing homelessness, substance use disorder, and mental illness, are likely to have a higher risk of developing COPD, and, furthermore, experience barriers to healthcare access and consequently poorer outcomes. Objective This study aims to assess COPD prevalence and impact of opportunistic screening among hospitalized patients who are in contact with hospital social nurses. These patients constitute a group of patients with a high prevalence of psychiatric and somatic diseases, substance use, low life expectancy, and are socially marginalized. Methods The present prospective longitudinal study includes a clinical examination at baseline. Participants will have spirometry done and participate in interviews regarding risk factors, socioeconomic conditions, and respiratory symptoms. The 5-year follow-up assessment incorporates data from baseline and register data over the five years, including information on morbidity, use of COPD medication, hospital contacts, mortality, and socioeconomic factors. Anticipated results Referral for further diagnostic work-up and management after the screening, including COPD treatment and smoking cessation support, is expected to improve survival rates. As the study is still enrolling patients there are no preliminary findings. Trial Registration The study is registered at ClinicalTrials.gov, NCT04754308 with study status: “enrolling”

Publisher

Research Square Platform LLC

Reference23 articles.

1. 2022. 2023 Global Initiative for Chronic Obstructive Lung Disease, available from www.goldcopd.org, published in Deer Park, IL, USA, https://goldcopd.org/wp-content/uploads/2023/03/GOLD-2023-ver-1.3-17Feb2023_WMV.pdf (accessed December 5, 2023).

2. Defining and targeting health disparities in chronic obstructive pulmonary disease;Pleasants RA;Int J Chron Obstruct Pulmon Dis,2016

3. Opportunities to diagnose chronic obstructive pulmonary disease in routine care in the UK: a retrospective study of a clinical cohort;Jones RCM;Lancet Respir Med,2014

4. Early detection of COPD in general practice;Ulrik CS;Int J Chronic Obstr Pulm Dis,2011

5. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary;Vogelmeier CF;Am J Respir Crit Care Med,2017

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