The osteoporosis diagnosis and treatment gaps and risk factors among women aged ≥50 years

Author:

Shahrousvand Shokouh1,Ostovar Afshin2,Fahimfar Noushin2,Khalagi Kazem2,Mansourzadeh Mohammad Javad2,Mansournia Mohammad Ali1,Sanjari Mahnaz2

Affiliation:

1. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical, Tehran, Iran

2. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Abstract Background Despite the availability of diagnostic equipment and effective drugs to diagnose and treat osteoporosis, only a minority of women are cared. The aim of this study was to investigate of the osteoporosis care gaps among postmenopausal women. Methods This cross-sectional observational study in one the province of Iran, collected data from women aged ≥ 50 years. Initially, participants were surveyed through FRAX. Then, a questionnaire was developed in 3 concepts (socioeconomic, diagnosis and medication initiation). Medication adherence was assessed using the validated OS-MMAS-8 questionnaire. Results A total of 998 women with a mean age of 64.6 ± 10.4 participated in this study. Overall, 346(34.6%) women were at high risk of fragility fractures through FRAX. 130(37.5%) women at high fracture risk underwent BMD, and 109 (31.5%) were diagnosed with osteoporosis. 44 (44.9%) patients adhere to the treatment and 54 (55.1%) patients did not. Overall, 9(20.5%), 35(79.5%) and 0 had low, medium, and high OS-MMAS-8 scores. The diagnosis and treatment gaps were 68.5% and 71.6%, respectively. Older age (OR = 0.97, 95%CI: 0.94–1.00, P =0.090), elementary education (OR = 4.80, 95%CI: 1.65–13.99, P = 0.004) and awareness of OP (OR = 6.03, 95%CI: 3.38–10.73, P < 0.001) were associated with diagnosis gap. Also, rural residence (OR = 0.45, 95%CI: 0.14–1.42, P = 0.175) and awareness of OP (OR = 4.34, 95%CI: 0.88–21.30, P = 0.071) is an independent risk factor for treatment gap. Conclusions There is a large OP care gap in women aged ≥ 50 years at increased risk of FF in Iran. Identification and assessment women at high fracture risk is effective in improving care of osteoporosis.

Publisher

Research Square Platform LLC

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