Dokdo sea lion Zalophus japonicus genome reveals its evolutionary trajectory before extinction

Author:

Kim Jungeun1,Blazyte Asta2,Choi Jae-Pil1,Kim Changjae3,Sharko Fedor4,Jeon Sungwon3,Kim Eun-Mi5,Sohn Hawsun5,Lee Jong Hee5,Kim Hyun Woo5,Yoo Mi Hyun6,Lee Kyunglee5,Nedoluzhko Artem4,Bhak Jong1

Affiliation:

1. Genome Research Foundation

2. Korean Genomics Center (KOGIC), Ulsan National Institute of Science and Technology (UNIST)

3. Clinomics, Inc

4. European University at Saint Petersburg, Saint Petersburg

5. National Institute of Fisheries Science

6. Conservation and Health Center

Abstract

Abstract

Background The Dokdo sea lion (Zalophus japonicus), commonly referred to as Gangchi in Korea also known as the Japanese sea lion, was endemic to the Northwest Pacific coast before becoming extinct in the 1950s. Little is known about its origins and speciation compared to other Otariidae species or how the rapid decline affected the species’ genetic diversity. Results To raise the Dokdo sea lion from this relative obscurity, we sequenced DNA from 16 Z. japonicus’ bone fragments, obtained from Dokdo and Ulleungdo islands in Korea. Our genome-wide SNP-based analyses establish Z. japonicus as the earliest diverged species within its genus, significantly redefining its evolutionary relationship with the California (Z. californianus) and Galapagos (Z. wollebaeki) sea lions. Our research further elucidates the phylogeny of Z. japonicus, shedding light on the complexity of the genetic isolation process within its genus that was prompted by the geographic isolation of the three populations of Zalophus ancestral stock. Conversely, the genetic signature of Dokdo sea lion genome can be modeled as an evolutionary pathway involving gene flow from Otariidae species with shared range. In addition, we discovered, population decline of the Z. japonicus started already over 1,000 years ago, however, Z. japonicus genome maintained a relatively high heterozygosity despite nearing extinction. Conclusions Our genome-scale analysis has eliminated ambiguity in the phylogeny of Z. japonicus and shed light on the evolutionary pathways underlying its speciation and the genetic diversity before its extinction. Broadly, this study highlights the importance of genome-scale analysis for the extinct marine megafauna to elucidate the complexity of their gene flow and subsequent genetic diversities among extant species. Furthermore, this study offers retrospective genomic insights into the extinction process of a carnivorous marine mammal, information that could aid conservation efforts towards extant Otariidae species.

Publisher

Springer Science and Business Media LLC

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3. The First Population Simulation for the Zalophus japonicus (Otariidae: Sea Lions) on Dokdo, Korea;Lee Y-J;Journal of Marine Science and Engineering,2022

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