Impacts of Pediatric Home Mechanical Ventilation on Child and Family Health-Related Quality of life: A Scoping Review Protocol

Abstract

Abstract Background The purpose of this review is to examine and summarize existing literature on pediatric invasive mechanical ventilation in the home environment to understand the health-related quality of life (HRQOL) of the child as well as the health-related family quality of life (FQOL). The use of invasive home mechanical ventilation is increasing for children with chronic respiratory conditions. Implementing in-home mechanical ventilation requires tremendous family and nursing support and impacts both the child’s quality of life and the family's quality of life. Methods Five databases will be searched using keywords and controlled vocabulary to identify relevant studies: Ovid Medline, Embase, Scopus, and Cochrane Library. Articles will meet inclusion criteria if they include primary research studies of children or families of children utilizing invasive home mechanical ventilation at home and assess quality of life. Children and young adults aged 0–25 years will be included. We exclude studies of hospitalized children, studies focused solely on healthcare professional experiences or clinical outcomes, and those focused on the period surrounding discharge from admission for tracheostomy placement. No date or language limits will be applied to the search. During screening, we will consider only English-language studies. Two independent reviewers will screen studies at the title/abstract and full-text levels. Two independent reviewers will extract data from relevant studies. Disagreements will be resolved by an independent third reviewer. Findings will be presented in tables and figures along with a narrative summary. Discussion This scoping review seeks to update the current literature and provide a more descriptive report of the factors that impact health-related quality of life in the presence of pediatric home mechanical ventilation. Systematic Review Registration Open Science Framework https://doi.org/10.17605/OSF.IO/6GB84