Predictive Value of acoustic cardiography for post-PCI early ventricular remodeling in acute myocardial infarction patients

Author:

Wang Wei﹣Wei1,Hao Hai-Zhen2,Fan Ting﹣Ting1,Yue Jia1,Wang Ming﹣Yang3,Chen Mo﹣Shui2,Deng Guo-lan4,Si Liang﹣Yi1,Zhang Fu﹣Wei1

Affiliation:

1. third affiliated Hospital of Chongqing Medical University

2. Haikou City People's Hospital

3. Peoples Hospital of Jiangbei District

4. The First Affiliated Hospital of Chongqing Medical University

Abstract

Abstract To investigate the clinical value of SDI,EMATc,BNP in the predictive of post-PCI early ventricular remodeling (EVR) in patients with acute myocardial infarction (AMI). 161 patients with asymptomatic acute anterior wall myocardial infarction after PCI were involved; BNP and acoustic cardiography were performed in pre-operation, Color Doppler echocardiography was performed after 72 hours. The patients were divided into two groups, which were the EVRgroup (EF% < 50%, EVR) and the normal left ventricular systolic function group (EF% ≥ 50%, Non- EVR). EMATc、SDI、BNP were independent risk factors for post-PCI EVRin patients with AMI [SDI (OR 15.924, 95% CI 3.649-69.491, p≤0.001) ,EMATc (OR 2.319, 95% CI 1.447-3.719, p<0.001 ) and BNP (OR 1.075, 95% CI 1.018-1.134,p=0.009)]. The area under the ROC curve (AUC) for EMATc was 0.89, with an optimal cutoff point of 12.2, EMATc produced a sensitivity of 80% and a specificity of 83%; whereas, with an optimal cutoff point of 100pg/ml, BNP produced a sensitivity of 46% and a specificity of 83%. EMATc、BNP、SDI have good predictive value for the occurrence of EVR in patients with asymptomatic acute anterior wall myocardial infarction after PCI.

Publisher

Research Square Platform LLC

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