Early warning of potential epidemics: A pilot application of an early warning tool to data from the pulmonary clinic of the university hospital of Thessaly, Greece

Author:

Meletis Eleftherios1,Poulakida Irene2,Perlepe Garyfallia2,Katsea Asimina2,Boutlas Stylianos2,Papadamou Georgia2,Gourgouliannis Konstantinos2,Kostoulas Polychronis1

Affiliation:

1. Faculty of Public and One Health, University of Thessaly

2. Respiratory Medicine Department, University of Thessaly School of Medicine, University Hospital of Larissa

Abstract

Abstract This paper describes a pilot application of the Epidemic Volatility Index (EVI) to data from the pulmonary clinic of the University Hospital of Thessaly, Greece, for monitoring respiratory infections, COVID-19, and flu cases. EVI, a simple and easily implemented early warning method based on the volatility of newly reported cases, exhibited consistent and stable performance in detecting new waves of epidemics. The study highlights the importance of implementing early warning tools to address the effects of epidemics, including containment of outbreaks, timely intervention strategies, and resource allocation within real-world clinical settings as part of a broader public health strategy. The results presented in the figures demonstrate the association between successive early warnings and the onset of new waves, providing valuable insights for proactive decision-making. A web-based application enabling real-time monitoring and informed decision-making by healthcare professionals, public health officials, and policymakers was developed. This study emphasizes the significant role of early warning methods in managing epidemics and safeguarding public health. Future research may explore extensions and combinations of multiple warning systems for optimal outbreak interventions and application of the methods in the context of personalized medicine.

Publisher

Research Square Platform LLC

Reference23 articles.

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2. World Health Organization (2021). Q&A on Coronaviruses (COVID-19). Available online (accessed on 20 June 2023)

3. Heffernan, R., Mostashari, F., Das, D., Karpati, A., Kulldorff, M., & Weiss, D. (2004). Syndromic surveillance in public health practice, New York City.

4. Syndromic surveillance practice in the United States: findings from a survey of state, territorial, and selected local health departments;Buehler JW;Advances in Disease Surveillance,2008

5. Shaman, J., & Karspeck, A. (2012). Forecasting seasonal outbreaks of influenza. Proceedings of the National Academy of Sciences, 109(50), 20425–20430.

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