Abstract
Abstract
Background: Polycythemia vera (PV), belonging to the myeloproliferative disorder, refers to the apparent overproduction of red blood cells. This pathological change culminates in blood hyperviscosity, which causing pregnant women with high risk of thrombosis. In this study, we introduced a rare case about a pregnant woman with PV in China.
Case summary: In this case report, we summarized the process of diagnosis and treatment about the pregnant woman with previously diagnosed PV during her gestation time. The first onset of this disease was in her twenty-second. She was supplied with hydroxyurea and interferon and got symptoms relieve. But she didn’t undergo regular treatment after that. She was hospitalized during gestation in her thirty-first, treated with regular administration of phlebotomy, aspirin (100mg), and low molecular weight heparin (LMWH). Finally, the patient delivered a healthy newborn after the cesarean.
Conclusion: Early diagnosis and intervention can effectively prevent pregnancy complications. Flexible control of hematocrit levels combined with anticoagulation contributes to improving pregnancy outcomes.
Publisher
Research Square Platform LLC
Reference7 articles.
1. Myeloproliferative disease in pregnancy and other management issues;Barbui T;Hematol Am Soc Hematol Educ Program,2006
2. Leukemias and lymphomas: time trends in the UK, 1984-93;McNally RJ;Cancer Causes Control,1999
3. Pregnancy and its management in the Philadelphia negative myeloproliferative diseases;Harrison C;Br J Haematol,2005
4. The management, outcome, and postpartum disease course of 41 pregnancies in 20 women with polycythemia vera;Wille K;Eur J Haematol,2021
5. Polycythemia vera: historical oversights, diagnostic details, and therapeutic views;Tefferi A;Leukemia,2021