Abstract
Skin diseases continue to affect human health and cause a significant disease burden on the healthcare system.We aimed to report the changing trends in the burden of skin disease in China from 1990–2019, Which has an important role in developing targeted prevention strategies. We applied Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 analytical tools to calculate the age-standardized Prevalence and Incidence rates in 2019, number of YLDs and agestandardized YLD rate from 1990 to 2019 of skin and subcutaneous diseases, notifiable infectious skin diseases and skin tumors in China. Among the skin and subcutaneous diseases in China in 2019, dermatitis contributed to the greatest years lived with disability (YLD) (2.17 million, 95% uncertainty interval[UI]: 1.28–3.36). Age-standardized YLD rates for leprosy decreased from 0.09 (95%UI: 0.06–0.13) in 1990 to 0.04 (95%UI: 0.03–0.06) in 2019; the proportional decrease was 55.56% over 30 years. Age-standardized YLD rates for HIV and sexually transmitted infections increased by 26% during the same time period. Age-standardized YLD rates for non-melanoma skin cancer increased at a much higher rate than melanoma between 1990 and 2019. Dermatitis and scabies continue to have an important role in the burden of skin and subcutaneous disease burden in China. The burden of non-melanoma cell cancer has increased most significantly over the past three decades.