Navigating genitourinary tuberculosis: lessons from a 2023 case

Author:

Ospina Natalia Ramos1,Tello Sofia Alexandra Montes1,Vélez John Harold Suarez2,Goez José Fernando García1

Affiliation:

1. Fundación Valle del Lili

2. Universidad Icesi

Abstract

Abstract

Background: Genitourinary tuberculosis (GU-TB), an extrapulmonary manifestation of Mycobacterium tuberculosis (Mtb) infection, often presents insidiously, posing diagnostic challenges and leading to progressive tissue destruction, chronic kidney disease, and urogenital dysfunction. Case presentation: We report a case of a patient initially diagnosed with endometriosis due to dysmenorrhea and chronic pelvic pain. Despite multiple surgical interventions, symptoms worsened. Misdiagnoses of urinary infections resulted in ineffective treatments. Subsequent testing revealed Mtb, prompting a six-month regimen of four-drug therapy (2HRZE/4HR), leading to significant improvement. Conclusion – take away lesson(s): This case underscores the importance of considering GU-TB in patients with persistent urogenital symptoms, even with initial negative tests. It emphasizes the necessity of a multidisciplinary approach and consideration of uncommon conditions for successful outcomes in complex scenarios.

Publisher

Research Square Platform LLC

Reference24 articles.

1. World Health Organization. Global Report TB 2022 [Internet]. 2022. Accessed on: March 18, 2024. https://www.who.int/teams/global-tuberculosisprogramme/tb-reports/global-tuberculosis-report-2022.

2. Instituto Nacional de Salud. Informe de evento Tuberculosis - A período epidemiológico XIII de 2023 [Internet]. 2023. Accessed on: March 18, 2024. https://www.ins.gov.co/buscador-eventos/Informesdeevento/TUBERCULOSIS%20PE%20XIII%202023.pdf.

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4. Extrapulmonary tuberculosis;Sharma SK;Expert Rev Respir Med,2021

5. Rapid diagnosis of tuberculosis through the detection of mycobacterial DNA in urine by nucleic acid amplification methods;Green C;Lancet Infect Dis,2009

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