Association between ABO blood group and preeclampsia in pregnant women

Abstract

Abstract Objective: To explore the correlation between maternal ABO blood group and preeclampsia. The results maybe used as the basis for the clinical prevention and treatment of preeclampsia. Methods: A case-control study was conducted, and 248 pregnant women with preeclampsia (PE group) and 248 normal pregnant women (control group) were included from October 1, 2016 to October 1, 2017. Compare the general condition of pregnant women in both groups. Compare the differences in the occurrence of preeclampsia in pregnant women with different blood groups. Compare the differences in triglycerides and cholesterol with different blood groups in the preeclampsia group. Results: There were statistically significant differences in age, pre-pregnancy BMI, gestational week, cholesterol and triglycerides between the PE group and the control group. However, there was no significant difference in the height of the two groups. Non-O blood groups were significantly more common than the O blood group in the PE group (59.1% V 28.9%). In contrast, in the control group, O blood group was significantly more common than the non-O blood groups (71.1% V 40.9%). In the PE group, non-O blood pregnant women had significantly higher triglyceride and cholesterol level than O blood pregnant women. Conclusion: Pregnant women with non-O blood groups have an increased risk of preeclampsia. Elevated blood lipids may contribute to the increased risk of preeclampsia in non-O blood group pregnant women.