Affiliation:
1. Chang Gung Memorial Hospital
2. Taipei Municipal Wan-Fang Hospital, Taipei Medical University
Abstract
Abstract
Introduction
Peptic ulcers are caused by unbalanced acid production, and proton pump inhibitors (PPIs) in recent decades have helped to treat peptic ulcers effectively. Meanwhile, the incidence of perforated peptic ulcer (PPU) persists and has a high mortality rate if there is no adequate management. Primary closure with a modified Graham’s patch was well performed in early detected PPU with a small size < 2 cm. A laparoscopic approach for PPU was prescribed for decades with proven feasibility and safety. We introduced an effective technique combined with barbed suture and modified Graham’s patch, which can reduce the surgical time without significantly increasing morbidity and mortality compared with traditional interrupted suture.
Patients and method
We retrospectively collected data from 2014/1 to 2020/12 in Keelung Change Gung Memorial Hospital, and a total of 154 patients receiving laparoscopic repair of PPU were included. There were 59 patients in the V-loc group (V group) and 95 patients in the P group.
Results:
The V group had a significantly shorter operation time than the P group (96.93 ± 22.14 mins vs. 123.97 ± 42.14, P < 0.001). Ten patients suffered from morbidity greater than the Clavien‒Dindo classification (CDC_ class 4 (5 from V group, and 5 from P group). Three patients with leakage were reported. Two patients were in the V group, and one patient was in the P group (p = 0.432).
Conclusion
Laparoscopic repair with barbed suture and modified Graham’s patch provides a simple and effective technique in the management of acute abdomen. This technique can be easily performed by experienced surgeons and trainees in minimally invasive surgery without affecting patient safety.
Publisher
Research Square Platform LLC