Abstract
Objective: To summarize the clinical experience of a case report of pancreaticoduodenectomy (PD) with en bloc celiac axis (CA) resection for locally advanced pancreatic cancer.
Methods: Clinical data of one patient with locally advanced pancreatic cancer who underwent pancreaticoduodenectomy with en bloc celiac axis resection after neoadjuvant chemotherapy and embolization of the proper hepatic artery in the Department of Hepatopancreatobiliary Surgery of the First Affiliated Hospital of Ningbo University in May 2023 were retrospectively analyzed.
Results: This case was operated smoothly with an operative time of 535 min, and intraoperative bleeding of about 800 ml. Only short-term elevation of hepatic aminotransferase appeared in the postoperative period, which was improved by hepatoprotective and symptomatic treatments, and was discharged from the hospital at 20 days postoperatively, and no tumour recurrence has occurred in the follow-up so far.
Conclusion: In patients with locally advanced pancreatic cancer with simultaneous invasion of the celiac trunk, common hepatic artery and hepatic innominate artery, total pancreaticoduodenectomy with en bloc celiac axis resection is safe and feasible in cases where neoadjuvant chemotherapy is effective and after establishing hepatic collateral circulation by preoperative embolization of the hepatic innominate artery. Meanwhile, more cases in more centers are needed to validate this conclusion.