Affiliation:
1. UWA: University of Western Australia
2. Sir Charles Gairdner Hospital
Abstract
Abstract
Background
Radiotherapy is an essential component of cancer treatment, but healthy tissues can be exposed to out-of-field doses, potentially causing adverse effects and secondary cancers. This study investigates peripheral doses outside the electron beam applicator in an Elekta Versa HD linear accelerator.
Methods
Peripheral doses outside the electron applicator were measured using 6, 9, and 12 MeV beams at their respective maximum dose depths while maintaining a 100 cm source-to-surface distance. Measurements employed EBT3 films within solid water phantoms. The influence of field size on penumbra width and peripheral doses were examined using various cutouts (6 x 6 cm², 10 x 10 cm², and a 5 cm diameter circle) within a 10 × 10 cm² applicator, with gantry and collimator angles set to 0 degrees. Additionally, the impact of collimator angles on penumbra width and peripheral doses was explored, enhancing the understanding of dose distribution. Measured profiles were also compared with those calculated using Monaco treatment planning system.
Results
Findings showed that both penumbra width and peripheral dose values increased with energy across different field sizes and collimator angles. Root Mean Square Deviation (RMSD) analysis indicated deviations of 1.8 mm for penumbra and 1.1% for peripheral doses between measured profiles and Treatment Planning System (TPS) predictions for all field sizes. Notably, peripheral doses remained below 5% of the maximum dose at distances ranging from 10 to 15 mm away from the field edges, suggesting the potential for implementation of supplementary shielding strategies.
Conclusion
This study highlights the critical importance of considering peripheral doses in radiotherapy, emphasizing the need to evaluate the impact on healthy tissues outside the primary treatment area to ensure patient safety and mitigate long-term treatment-related side effects. The findings underscore the necessity of implementing appropriate measures to minimize peripheral doses.
Publisher
Research Square Platform LLC
Reference27 articles.
1. Radiation induced secondary malignancies: a review article;Dracham CB;Radiation Oncol J,2018
2. Regulating exposure of the lens of the eye to ionising radiations;Thorne M;J Radiol Prot,2012
3. Khan FM, Gibbons JP (2014) Khan's the physics of radiation therapy. 5th Edition ed. : Lippincott Williams & Wilkins
4. Podgoršak EB (2006) Radiation physics for medical physicists. Biological and medical physics, biomedical engineering. Springer, Berlin;
5. Quantification and reduction of peripheral dose from leakage radiation on Siemens Primus accelerators in electron therapy mode;Yeboah C;J Appl Clin Med Phys,2010