Comprehensive IR and NMR research of a newly Synthesized derivative of Imidazole–1,3,4–Oxadiazole

Abstract

Abstract Background Due to their critical applications in several domains or diseases, the compounds imidazole and oxadiazole have attracted a lot of interest. Oxadiazole is an anti-tussive, anti-inflammatory, anaesthetic, vasodilator, anti-helmintic, anti-allergic, and anti-platelet drug. Imidazole is an antifungal, anti-protozoal, and antihypertensive drug. The purpose of this study is to synthesize and characterize the derivative by using FTIR and 1H-NMR. The derivatives synthesis was completed. Ethyl 2-(1H-imidazol-1-yl) acetate is made in the first stage, and 2-(1H-imidazol-1-yl) acet-hydrazide is made using this Ethyl 2-(1H-imidazol-1-yl) acetate. The subsequent addition of 3-methoxybenzaldehyde followed by the addition of acetic anhydride led to the formation of the desired compounds. Studies using FTIR were conducted. Studies using 1H-NMR were also carried out. Result As a result, IR and 1H-NMR were used to characterise the synthesised material. A synthetic derivative's structure was established. Conclusions In conclusion, imidazole serves as the starting ingredient for the synthesis. The IR and NMR investigation was appropriately conducted, and this technique yields satisfactory results.