Development of a Precision Medicine Competency Framework for the Therapeutics Industry

Abstract

Abstract INTRODUCTION: The successful adoption of precision medicine relies on the development of effective treatments and judicious utilization within a supportive healthcare system. Embracing a learning healthcare capability will be crucial to navigating the disruptions arising from rapid scientific and technological innovation. AIM: to build a Precision Medicine (PM) competency framework that can be used across the Medical Technology and Pharmaceutical (MTP) industries to build a confident and capable workforce, support cross-disciplinary work and collaboration, and instil a continuous learning mindset. METHODOLOGY: A desktop research review of current literature, curriculum, and healthcare trends identified a core set of domains and subdomains related to precision medicine competencies. A survey was distributed to the Industry Genomics Network Alliance (InGENA) members in 2021 to confirm the relevance and applicability of the domains and subdomains to their current work practice and their expected work practice in 5 years’ time. RESULTS: Four domains were identified: medical science and technology; translational and clinical application; governance and regulation and professional practice. Each domain has a series of subdomains and patient needs were integrated across all four of the domains. Survey results confirmed the applicability of these domains to the MTP industry. CONCLUSION: The Framework was well accepted by industry, with a strong interest from related disciplines including allied health professionals. Given the pace of change this framework will need regular review and updating. The principles can be used to define frameworks for other technologies such as Cell and Gene Technologies (CGT) and Regenerative Medicines (RM).