The association between peptic ulcer disease and physical activity in Wuwei cohort of northwest China: A cross-sectional study

Abstract

Abstract Although the incidence of peptic ulcer disease (PUD) is gradually decreasing, it is still a common upper gastrointestinal disease worldwide. The relationship between PUD and physical activities was evaluated in Wuwei cohort. Ultimately 4612 patients were included. The status of PUD was confirmed by gastroscopy and the metabolic equivalents of task (MET) scores were evaluated through questionnaires. In addition to the overall analysis, stratified regression analysis was performed based on body measurement indice and age. Female participants in moderate level group had a lower prevalence of gastric ulcer (GU) (OR: 0.58, 95% CI: 0.36, 0.93). After further adjusting, the same conclusion could still be reached (model 2 OR: 0.53, 95% CI: 0.28, 0.99). In stratified analysis based on body mass index (BMI) and waist circumference (WC), moderate physical activity was associated with a reduction in the risk of GU among females. In stratified analysis by age, participants with age < 60 in moderate and high level groups had a lower risk of GU. The prevalence of gastric ulcer in female participants with moderate physical activity was lower. In addition, females under 60 in the high level group had a lower risk of PUD.