Emergence of SARS-CoV-2 Spike Escape Mutation Q493R After Bamlanivimab/Etesevimab Treatment for COVID-19-Reference-Cited by-同舟云学术

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Emergence of SARS-CoV-2 Spike Escape Mutation Q493R After Bamlanivimab/Etesevimab Treatment for COVID-19

Published:2021-05-18 Issue: Volume: Page:
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Author:

Focosi Daniele¹,Novazzi Federica²,Genoni Angelo³,Dentali Francesco³,gasperina Daniela Dalla³,Baj Andreina³^ORCID,Maggi Fabrizio³

Affiliation:

1. North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy

2. Laboratory of Microbiology, ASST Sette Laghi, Varese, Italy

3. Department of Medicine and Surgery, University of Insubria, Varese, Italy

Abstract

Abstract We report here the first in vivo selection of a Spike mutation (Q493R) conferring simultaneoius full resistance to both bamlanivimab and etesivimab.

Publisher

Research Square Platform LLC

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The biological and clinical significance of emerging SARS-CoV-2 variants;Nature Reviews Genetics;2021-09-17

2. COVID-19 convalescent plasma and randomized clinical trials: explaining conflicting outcomes and finding signals of efficacy;2021-09-15

3. SARS-CoV-2 Variants: A Synopsis of In Vitro Efficacy Data of Convalescent Plasma, Currently Marketed Vaccines, and Monoclonal Antibodies;Viruses;2021-06-23

4. Biparatopic sybody constructs neutralize SARS-CoV-2 variants of concern and mitigate emergence of drug resistance;2020-11-10

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