Odontogenic factors that affect the maxillary sinus Schneiderian membrane and their relationship to chronic sinonasal symptoms

Abstract

AbstractBackground:Odontogenic sinusitis is a common maxillary sinus disease. It develops due to the violation of the Schneiderian membrane due to pathological, iatrogenic, or traumatic causes from dental and dentoalveolar structures. This study aimed to investigate local and systemic factors associated with Schneiderian mucosal thickening (MT) in patients referred for post-endodontic diseases and their relationship with chronic sinonasal symptoms.Methods:A retrospective evaluation of cone-beam computed tomography (CBCT) scans of patients referred for evaluation of post-endodontic diseases was performed. Mucosal thickening in relation to the affected tooth was measured in the coronal section in millimeters at the maximum area perpendicular to the bone. Based on this measurement, the sinus floor was categorized for MT as present (>1 mm) or absent (<1 mm). The sociodemographic and clinical characteristics of the study participants were assessed and compared according to the presence or absence of MT. Furthermore, the relationship between odontogenic sinusitis and chronic sinonasal symptoms was assessed using a Chronic Sinusitis Survey.Results:Male patients had a higher MT than female patients. The presence of periapical lesions and inadequate endodontic treatment were significantly associated with MT. The multivariate logistic regression model showed that the presence of PA lesions increased the odds of MT by approximately 2.5 times (p = 0.028), and nasal obstruction was significantly higher in patients diagnosed with mucosal thickness at different time of follow-ups period (p = 0.018).Conclusions: MT was 2.4 times more likely in the presence of periapical pathosis, and nasal obstruction was the most significant factor associated with the presence of MT.