Clinical predictive role of Mayo adhesive probability score in nephrectomy and adrenalectomy：A Systematic Review and Meta-analysis

Abstract

Abstract Purpose This study aimed to determine the clinical predictive role of Mayo adhesive probability (MAP) score in nephrectomy and adrenalectomy. Methods Publications were searched in PubMed, Web of Science, and Embase. Pooled analysis of MAP predictive role of perioperative outcomes including operative times (OT), estimated blood loss (EBL), warm ischemia time (WIT), length of stay (LOS), and complication rate was performed. Weighted mean differences (WMDs) with 95% confidence intervals (CIs) for continuous data and Odds ratio (ORs) with 95% Cis for dichotomous data were considered the effect size. Statistical significance was defined as P-value < 0.05. Results A total of 10 eligible studies including 3200 patients undergoing nephrectomy or adrenalectomy were included. Pooled results of 10 studies showed that OT in high MAP score group were significant longer than those in low MAP score group (WMD = 18.58, 95% CI: [11.44, 25.73], P < 0.00001). Pooled results of 7 studies showed that EBL in high MAP score group were significant greater than those in low MAP score group (WMD = 38.50, 95% CI: [20.44, 56.57], P < 0.0001). Pooled results of 5 studies showed that there was no significant difference on WIT between high MAP score group and low MAP score group (WMD = 0.58, 95% CI: [-0.34, 1.51], P = 0.22). Pooled results of 6 studies showed that there was no significant difference on LOS between high MAP score group and low MAP score group (WMD=-0.07, 95% CI: [-0.39, 0.25], P = 0.67). Pooled results of 7 studies showed that there was no significant difference on complication rate between high MAP score group and low MAP score group (OR = 0.79, 95% CI: [0.57, 1.11], P = 0.18). Conclusion The high MAP score predicts longer operative times and greater estimated blood loss. In other words, the MAP score could predict surgical complexity.