Endometrioid Carcinoma of the Ovarian Resembling Wolffian Tumor: a case report

Abstract

Abstract Background Endometrioid carcinoma is a common epithelial malignant tumor in the female reproductive system. It mainly occurs in the uterus, fallopian tubes, and ovaries. Endometrioid carcinoma reassembling Wolffian tumor, similar to Wolffian tumor, is a type of endometrial carcinoma with a very rare histological structure. At present, only 23 cases have been reported in domestic and foreign literature, of which 2 cases occurred in the ovary and 21 cases occurred in the fallopian tube lumen. Here, we report a case of endometrioid carcinoma of the ovarian resembling FATWO and review the literature. Case presentation A 65-year-old female patient presented with dysuria for one month. CT showed a pelvic mass. Macroscopically, the tumors form a solid mass with a gray-red to tan. Microscopically, the tumor was composed of tubular, balk and solid structures, among which many small crowded glands. The small and round tubular structure was composed of simple cuboidal epithelium, and eosinophilic secretions can be seen in the lumen. Immunohistochemical staining showed that CK-Pan, EMA, ER, PR, CK8/18 and CEA were positive in the tumor cells, but WT-1, PAX-8, TTF-1, GATA3, calretinin and α-inhibin negtive, wild-type P53, Ki67 index was 10%. The final diagnosis was endometrioid carcinoma of the ovary resembling Wolffian tumor. The patient was followed up for 1 year and 9 months without recurrence. Conclusions We review the previously published cases of endometrioid carcinomas of the resembling FATWO, and discuss the principal differential diagnosis of the tumor in the ovary.