Risk factors and preventive measures of intracranial infection after neurosurgery

Abstract

Abstract Objective To analyze the risk factors of postoperative intracranial infection in neurosurgery, so as to provide reference for prevention and treatment of postoperative intracranial infection in neurosurgery. Methods 156 patients who underwent postoperative intracranial infection in neurosurgery of our hospital from January 2016 to April 2022 were analyzed retrospectively. Pair principle was adopted, and the same number of cases from uninfected cases were selected as the control group; the clinical data of the two groups were statistically analyzed by SPSS22.0 software. Results Univariate analysis showed that primary disease, emergency operation, duration of operation, type of incision, operation mode, duration of indwelling drainage tube after operation, use of microscope during operation, whether to enter ICU, cerebrospinal fluid leakage after operation and secondary operation were the risk factors of postoperative intracranial infection (P < 0.05); multivariate logistic regression analysis showed that operation duration ≥ 4h, incision type, cerebrospinal fluid leakage and second operation were independent factors of postoperative intracranial infection (P < 0.05). Conclusion There are many risk factors for postoperative intracranial infection in patients from neurosurgery. It is necessary to take targeted preventive measures, such as shortening the operation time, treating cerebrospinal fluid leakage in time, avoiding secondary operation as much as possible, and using antibiotics prophylactically during perioperative period. These measures can effectively reduce the probability of postoperative intracranial infection in neurosurgery patients.