Affiliation:
1. Bu-Ali Sina University
Abstract
Abstract
A novel deep eutectic solvent (MTPPBr-PCAT-DES) was prepared from a one-to-one mole ratio of methyltriphenylphosphonium bromide (MTPPBr) and 3,4-dihydroxybenzoic acid (PCAT=protocatechuic acid) and characterized by various techniques such as FT-IR, TGA/DTA, densitometer, eutectic point, and 1H NMR. Then, it was used as a novel and capable catalyst for the synthesis of pyranopyrimidines from the multicomponent condensation reaction of barbituric acid, 4-hydroxycoumarin, and aromatic aldehydes in mild conditions, short reaction times, and high yields.
Publisher
Research Square Platform LLC
Reference50 articles.
1. Novel solvent properties of choline chloride/urea mixtures;Abbott AP;Chem. Commun.,2003
2. Novel choline-chloride-based deep-eutectic-solvents with renewable hydrogen bond donors: levulinic acid and sugar-based polyols;Maugeri Z;RSC Adv.,2012
3. de María, P. D. Ionic liquids, switchable solvents, and eutectic mixtures, in the application of green solvents in separation processes, 1st ed., Editors: F. Pena-Pereira, M. Tobiszewski, ISBN: 9780128052976, Elsevier 139–154 (2017).
4. Comparison of deep eutectic solvents and solvent-free reaction conditions for aldol production;Milker S;Mol. Catal.,2019
5. Stereoselective organo-catalysed reactions in deep eutectic solvents: Highly tunable and bio-renewable reaction media for sustainable organic synthesis;Massolo E;Green Chem.,2016