Abstract
Objective: The aim of this retrospective case control study was to investigate the clinical characteristics and the outcomes of acute excerbations of chronic obstuctive pulmonary disease (AECOPD) patients between different gender.
Methods: We aim to collect the first hospitalization patients who were diagnosed as AECOPD between 1 January 2019 to 31 December 2021 from the general ward and intensive care unit in the hole hospital, Shanghai the Fifith Peoples Hospital, Fudan University. Demographic data, initial clinical symptoms, on admission vital signs, comorbidities, laboratory tests and imaging examination, treatment and the follow-up were compared between the two groups.
Results:The patients were followed up for 30 days, 90 days, 180 days after the discharge from the hospital, all these difference were not statistically significant in hospital readmissions and mortality(P＞0.05). The multivariate analysis incorporated seven factors according to the results of the univariate regression analysis, The results showed that readmission was independently associated with increased course of disease(P=0.032), combined with chronic pulmonary heart disease(P=0.011) , and combined with peptic ulcer(P=0.044). Conversely, gender were not retained(P=0.304).
Conclusion: The short-term readmission was independently associated with increased course of disease, combined with chronic pulmonary heart disease, and combined with peptic ulcer but not with sex.