Abstract
Background: Amnesia is a cognitive impairment that manifests as a deficit in the retrieval of previous memories and the acquisition of novel information. There is some evidence indicating that smoking might be linked to a greater likelihood of experiencing memory issues and cognitive decline, such as Amnesia. The purpose of this study was to explore the risk factors associated with Amnesia and the connection between smoking and Amnesia.
This population-based cross-sectional study
Methods: This population-based cross-sectional study was conducted at the baseline of the Hoveyzeh cohort study in adults aged 35-70 years in southwest Iran between 2016 and 2018. Information on socioeconomic factors, demographic characteristics, history of stroke, history of epilepsy, and history of head trauma was collected. We assessed the relationship between smoking and Amnesia. Multiple logistic regression was employed to account for potential confounding variables.
Results: The mean age of the participants was 48.8 ± 9.2 years, and 40.2% were male. The overall prevalence of Amnesia was 4.2% (95% CI 3.8–4.6). The odds of having Amnesia was significantly higher in smokers than nonsmokers (OR Adj=1.52 (95%CI:1.21–1.91)). Additionally, several other factors, including age, education level, type of residence, history of stroke, epilepsy, and history of trauma, were associated with Amnesia.
Conclusion: Our investigations revealed a direct correlation between smoking and Amnesia. To gain a more comprehensive understanding of the underlying mechanisms of these associations, it will be imperative to conduct future longitudinal studies.