Genital Mycoplasma and genital disorders among women of childbearing age in Franceville, South-Est Gabon.

Author:

Moghoa Kelly Hornelia Mbombe1,Onanga Richard1,Bignioumba Michelle1,Nzambe Jean Ulrich Muandze1,Lendamba Romeo Wenceslas1,Mouanga-Ndzime Yann1,Mahmoudou Saidou2,Mba Romuald Be2,Pecmann Klara2,Gafou Amahani1,Kassa Roland Fabrice Kassa1,Bisseye Cyrille3

Affiliation:

1. Centre Interdisciplinaire de Recherches Médicales de Franceville (CIRMF)

2. Centre de Recherches Médicales de Lambaréné (CERMEL)

3. University of Science and Technology of Masuku (USTM)

Abstract

Abstract Objective. This study evaluated the prevalence of Ureaplasma spp. and Mycoplasma hominis and their association with genital disorders (bacterial vaginosis, aerobic vaginitis, and vulvovaginal candidiasis). Methods. The IST2 kit identified genital mycoplasmas. Nugent score and microscopic observation of neutrophils and bacteria served to diagnose bacterial vaginosis and aerobic vaginitis. Chi-square or Fisher’s exact test served for statistical analysis. Results. The prevalence of M. hominis and Ureaplasma spp. was estimated at 2% and 41%, respectively, and Ureaplasma spp./M. hominis was 32%. The prevalence of BV, VVC, and AV was de 68%, 35%, and 54%, respectively. Group B Streptococcus (P=0.006, OR=0.41, 95% CI=0.22–0.77) (P=0.002, OR=0.30, 95% CI=0.14–0.63) was not associated with M. hominis, Ureaplasma spp./M. hominis respectively. Conclusion. This study reports a high prevalence of genital mycoplasmas. VVC, AV, and BV were frequently encountered, but the association with genital mycoplasmas was not statistically significant.

Publisher

Research Square Platform LLC

Reference38 articles.

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3. Genital mycoplasmas;Judlin P;Gynecol Obstet Fertil,2003

4. Mycoplasma hominis and Gardnerella vaginalis display a significant synergistic relationship in bacterial vaginosis;Cox C;Eur J Clin Microbiol Infect Dis,2016

5. Prevalence of Ureaplasma spp. and Mycoplasma hominis in healthy women and patients with flora alterations Tatiana;Rumyantseva T;Diagn Microbiol Infect Dis,2018

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