Effects of central pathway and postural control technique on stroke patients: a randomized controlled trial

Abstract

Abstract Objective We investigated the effects of central pathway and postural control (CPPC) technique on motor function, balance function, activities of daily living, degree of neurological deficit, nerve cytokine content and hemorheology indexes of stroke patients. Method 78 stroke patients were randomly divided into an experimental group added the CPPC technique on the basis of routine rehabilitation therapy and a control group receiving routine rehabilitation therapy. All interventions were 1 time / day for 50 days in both groups. Outcome measures were collected at baseline and post-intervention. The primary outcome measures included the National Institutes of Health Stroke Scale (NIHSS) and the Fugel-Meyer assessment scale (FMA). The secondary outcome measures included Berg Balance Scale (BBS), Tinetti Balance and Gait Analysis, Barthel Index (BI), neuronal cytokine content and hemorheological Indices. Result The results of this study show that NIHSS scores of the two groups decreased and FMA scores increased after treatment. Compared with before treatment, BBS score, Tinetti score and the scores of each item of BI scale of the two groups were increased, and there were significant differences between the two groups. The content of NT-3 and NGF in serum of the two groups increased and the hemorheology indexes of HBV, LBV, PV, HCT and fibrinogen decreased after treatment, and there were significant differences between the two groups. Conclusions The CPPC technique can alleviate limb dysfunction and motor limitation and can improve balance function, activities of daily life and blood circulation in stroke patients. The CPPC technique is a promising method for future neuropsychological research and can also be used in clinical treatment of stroke patients.