Chemical composition and biological activities Assessment (antioxidant, antimicrobial, anti-inflammatory and healing wounds activities) of crude extract of roots of Paeonia mascula subsp. atlantica (Coss.) Greuter & Burdet = (Paeonia algeriensis Chabert)
Author:
wafa Nouioua1,
sofiane Gaamoune1,
ouarda Djaout,
nouioua wafa1
Affiliation:
1. Ferhat Abbas University
Abstract
AbstractBackground:Paeonia algeriensisChabert is an Algerian endemic species habitually used by local people in traditional medicine. This study tried to express phytochemicals composition and biological activities of the species. CG/Ms was used to determine molecular composition, antioxidant activity was assessed by three tests (DPPH, reducing power and lipid peroxidation), antimicrobial activity was tested with four bacterial strains and one yeast, the anti-inflammatory activity was carried out by the human red blood cell (HRBC) membrane stabilization method and theIn-vivohealing wounds activity by excision model.Results:The result show a perfect antioxidant activity, a powerful antibacterial effect an important anti-inflammatory power at a low concentration and total healing wounds effect in just 13 days of experiment.Conclusions:The above results indicate that the roots ofPaeonia masculahave great potential in the development of new drugs.
Publisher
Research Square Platform LLC
Reference58 articles.
1. Stearn WT, Davis PH. (1984). Peonies of Greece. Goulandris Natural History Museum, Kifissia, Greece.
2. Plant List. (2013). Version 1.1. Published on the internet.
3. To be or not to be—the effect of nature conservation management on flowering of Paeonia mascula (L.) Miller in Israel;Ne'eman G;Biol Conserv,2003
4. Reconstructed Materia Medica ofthe medieval and Ottoman Al-Sham;Lew E;J Ethnopharmacol,2002
5. Gennadios PG. (1914). Phytological lexicon.