Efficacy of coagulation factor infusion combined with staged surgery in the treatment of moderate hemophilia A combined with kidney stone

Abstract

Abstract Background To date, there are few reports related to the treatment of patients with hemophilia combined with kidney stones, and there are no standardized treatment protocols for patients with hemophilia combined with kidney stones. Case presentation: This case report is of a 27-year-old male patient with hemophilia and left-sided renal calculi. He had severe back pain and bright red hematuria as a result of the disease. On urologic CT we found a left renal pelvic hematoma. The patient was treated with coagulation factors and staged surgery, and his kidney stones have now been cured. Conclusions Patients with hemophilia A are at high-risk for operation and the expense of transfusion of clotting factors is expensive, so strict indications for operation must be followed, otherwise operative treatment should be avoided. When dealing with patients with moderate hemophilia A combined with kidney stones, if they have ureteral obstruction, back pain, bright red hematuria, etc. If the patient's condition is good and medical conditions allow, operative treatment should be performed as soon as possible. If a patient has a pelvic hematoma and severe hematuria, in addition to the need to give the patient a clotting factor infusion, we can stage the surgery to reduce the risk of the associated surgery. The first period is to drain the pelvic hematoma to relieve the patient's hard and improve the patient's renal function, and also to prepare for the second period of lithotripsy. After the patient's general condition improves, then we can perform lithotripsy and try to remove the lithotripsy to reduce the bleeding caused by lithotripsy and ureteral stent.