New strategy for the synthesis of photo-crosslinkable polyalphaolefin resins and related biocompatible three-dimensional networks

Abstract

AbstractIn this research, functionalization of the easily available polyalphaolefin (PAO) based resins is accomplished by the copolymerization of 1-decene with 9-decenol through a facile cationic polymerization route. The resultantCo-oligomerwas further functionalized with acryloyl chloride to furnishMacromerproduct. The exact microstructure of synthesized and modified resins was explored via H-NMR, FTIR and GPC analytical methods. The PAO chains contain roughly 20 monomeric units in which three polymerizable C = C moieties could be embedded. The crosslinking ofMacromervia visible light irradiation in the presence of a photo-initiator system provided final fabricate. The effect of photo-initiator content on the cross-linking kinetics of the resin wasexplored using shrinkage strain measurement. The resulted three dimensional PAO (3D-PO) revealed hydrophilic nature with water contact angel of 65° and excellent cell viability of 93% in the MTT assay. This strategy starts from easily available α-olefin based monomers, employs a facile cationic polymerization procedure, enables modulation of the functional groups in theMacromerbackbone in order to make it photo-polymerizable, and holds great potential for tissue engineering applications.