Monkey pox-epidemiology, clinical presentation and transmission: A systematic review

Author:

Sharma Ashima1,Prasad Hari2,Kaeley Nidhi2,Bondalapati Aparna1,Edara Lokesh3,Kumar Y Ajay1

Affiliation:

1. Nizam’s Institute of Medical Sciences

2. All India Institute of Medical Sciences Rishikesh

3. Western Michigan University School of Medicine

Abstract

Abstract Background: The new zoonotic viral infection monkeypox is a global health issue. Our study aimed at studying the epidemiology, clinical presentation, complications, case fatality rate, and transmission among the present cases of monkeypox infection. Methods: Articles were searched in PubMed, Google Scholar, and Science Direct databases using the keywords 'Monkeypox' [MeSH] or 'Monkeypox virus (MeSH). Narrative reviews, conference abstracts, commentaries and articles in language other than English were excluded. Results: Among 2352 confirmed cases studied from published literature which account for approximately 4% of infected cases worldwide. Around 81.71% of patients have a bisexual or Men having Sex with Men (MSM) preference. Approximately 30.18 % of confirmed cases were HIV positive. Male sex was also identified as a risk factor in our review. Conclusion: As monkeypox human to human and human to animal transmission is rising. Researching preventive, clinicodemographic and therapeutic related to monkeypox is therefore crucial.

Publisher

Research Square Platform LLC

Reference43 articles.

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3. Antinori A, Mazzotta V, Vita S, Carletti F, Tacconi D, Lapini LE, et al. Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Eurosurveillance [Internet]. 2022 Jun 2 [cited 2022 Nov 30];27(22):2200421. Available from: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.22.2200421

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