Abstract
AbstractBackground Hepatitis B virus (HBV) infection is a global public health problem against which vaccination is recommended for all high-risk adults. HBV is highly endemic in Northern Uganda, however, there is a paucity of literature regarding HBV vaccine uptake and associated factors within the community in the region. In this study, we aimed to determine the level of HBV vaccine uptake and associated factors among adults in Gulu city, Uganda. Methods We conducted a community-based, cross-sectional study in Gulu city among eligible adults between March and May 2022. Data on HBV vaccination status and sociodemographic characteristics were collected using an interviewer-administered questionnaire. Full uptake of HBV vaccine was defined as receipt of all 3 recommended doses, and partial uptake for 1 or 2 doses. Multivariable logistic regression analysis was performed using STATA 16.0 to determine factors independently associated with HBV vaccine uptake. P < 0.05 was considered statistically significant. Results In total 360 participants were enrolled, of whom 212 (58.9%) were female, 183 (50.8%) were aged 30 years or younger, and 143 (39.7%) had attained tertiary education. Overall, 96 (26.7%) participants had full uptake of HBV vaccine and 73 (20.3%) had partial uptake. Factors that were statistically significantly associated with full uptake of HBV vaccine were; Good knowledge regarding HBV transmission (adjusted odds ratio (aOR) = 1.9, 95% Confidence Interval (CI) = 1.03 — 3.46, p = 0.040) and receiving health education on HBV vaccination (aOR = 4.4, 95% CI = 2.3 — 8.4, p < 0.001). Conclusions There is a low uptake of HBV vaccine in Gulu city. The Uganda Ministry of Health should correct misconceptions, create awareness of the severity of HBV infection through health education regarding HBV infection within the community in Gulu City; and set mechanisms to follow-up clients due for next HBV vaccination.
Publisher
Research Square Platform LLC
Reference37 articles.
1. AMMON A, REICHART PA, G. P. and L. R. P. (2000). Hepatitis B and C among Berlin dental personnel: incidence, risk factors, and effectiveness of barrier prevention measures. 407–413.
2. Low level of Hepatitis B knowledge and awareness among pregnant women;Abdulai MA;the Kintampo North Municipality: implications for effective disease control,2016
3. Factors Associated with the Completion of Hepatitis B Vaccine among University Students in Nigeria;Agbede CO;Global Journal of Medicine Research,2016
4. Factors associated with knowledge, attitude and practice related to hepatitis B and C among international students of Universiti Putra Malaysia;Ahmad A,2016
5. Ai O, An O. (2013). Hepatitis B Vaccination Uptake among Doctors in Benin City, Edo State, Community Medicine & Health Education Hepatitis B Vaccination Uptake among Doctors in Benin City, Edo State, Nigeria. (February). https://doi.org/10.4172/2161-0711.1000246.